Science & Research
The global battle against Type 2 diabetes has reached a critical juncture, with the World Health Organization
reporting a staggering 422 million adults affected worldwide. Amid this public health challenge, Focused Insulin
Therapy (FIT) emerges as a beacon of hope, poised to revolutionize diabetes care. This novel approach is the
greatest advance in diabetes care since the discovery of insulin, which transformed diabetes from a fatal
diagnosis into a manageable condition.
The FIT Protocol: A Legacy of Innovation
The FIT protocol stands on the shoulders of giants. Since the ground-breaking discovery of insulin over a
century ago, we have continued to seek advancements in diabetes treatment. FIT potentially represents the latest
leap forward, drawing from decades of research to offer a more nuanced approach to insulin administration.
The Mechanism of FIT
At its core, FIT is designed to mimic the natural fluctuations of insulin levels in a healthy body. By adapting
insulin delivery to the dynamic needs of patients, FIT offers a physiological approach to diabetes management,
potentially reducing the risk of hypoglycemia and other complications associated with static dosing schedules.
Let’s Dive into the Science
Since insulins first use on humans in the 1920’s we have taken a linear approach to treating high blood sugar.
When blood sugars elevate, we aid the body with a shot of insulin bringing the blood sugar back down. For the
patient it begins to feel like a game of Whack-a-mole, sugars go up and we whack it back down. Although
lifesaving and the standard of care for a century, this becomes exhausting for both the patient physically and
mentally as well as for their family watching their loved one’s health slowly decline. Understanding the intricate
dance of hormones within our body offers insight into the onset and progression of diabetes.
In a healthy state, the pancreas exhibits a rhythmic release of insulin from beta cells into the portal vein, with
pulses every 4 to 8 minutes, influenced by diet, physical activity, and stress levels. This mechanism ensures
insulin and glucagon, its counterpart from alpha cells, maintain a delicate balance, working in a beautiful inverse
relationship, alternating between activity and rest for insulin receptors.
As diabetes develops through its stages—insulin resistance, prediabetes, full-blown diabetes, and diabetes with
complications—the pancreas’s rhythm falters, leading to a relentless demand on both beta cells and insulin
receptors, akin to a mother overwhelmed by her children’s constant needs. This overstimulation causes insulin
receptors to become less sensitive, cellular fatigue sets in, and excess sugar begins to wreak havoc throughout
the body, manifesting as fatigue, mental cloudiness, headaches, thirst, weight gain, blurred vision, and slow
healing.
Neglecting these warning signs or merely masking them with medication can lead to severe consequences, such
as kidney failure, chronic wounds and potential amputations, neuropathy, vision loss, heart disease, strokes, and
even cancer.
However, we can coax the body toward equilibrium by emulating the pancreas’s natural rhythm. This approach
can take into remission the associated chronic conditions and symptoms, restore restful sleep, clarity of mind,
improved vision, and a rejuvenated sense of vitality. Ultimately, we observe a regression of diabetes itself,
decreasing reliance on medications, alleviating the constant burden of monitoring, and broadening dietary
choices, enhancing overall quality of life.
If you or someone you love are on the trajectory toward diabetes or are grappling with its impact, now is the
time to act. Embrace therapy that can potentially transform your life and steer you away from the path of chronic
disease.
Addressing Vascular Complications
A particularly grievous aspect of diabetes management is the treatment of vascular complications, such as non-
healing wounds and the risk of amputation. By optimizing insulin delivery, FIT aims to improve blood flow and tissue repair mechanisms, thereby addressing the root causes of these debilitating conditions. Through rigorous
clinical studies, we are on the cusp of demonstrating that FIT can not only manage diabetes but also take its
vascular effects into remission, offering hope to those facing the specter of amputation.
Neuropathy and Organ Function: A Renewed Focus
The ramifications of diabetes extend beyond blood sugar levels, often leading to neuropathy and compromised
kidney and renal functions. FIT’s personalized insulin management is hypothesized to alleviate the nerve
damage that results in neuropathy and bolster organ function. Our studies are designed to investigate these
outcomes, providing a foundation of evidence for the protocol’s efficacy in taking some of the most challenging
aspects of diabetes into remission.
The Economic Implications of Advanced Diabetes Management
The financial strain imposed by late-stage diabetic conditions on both the healthcare system and affected
families is profound. Hospitalizations, long-term care for chronic wounds, dialysis for kidney failure, and other
related treatments contribute to a healthcare crisis of escalating costs. By preventing these conditions through
the proactive management of diabetes, FIT seeks to diminish these economic burdens significantly.
A Vision for Cost-Effective Care
Our vision extends beyond medical triumphs; it encompasses a strategy to alleviate the financial pressures on
our healthcare infrastructure. By proving that FIT can stave off the expensive treatments typically associated
with advanced diabetes, we are advocating for a system prioritizing cost-effective care and improved quality of
life for patients.
Precision Diabetes Care: A Synergistic Approach
While FIT remains our primary focus, we recognize the burgeoning potential of Precision Diabetes Care to
enhance our efforts. This innovative concept, though less central to our narrative, complements the FIT protocol
by offering a personalized health monitoring system through a home-based minilab.
The Role of the Minilab in Enhancing FIT
The minilab is an adjunct tool, allowing patients to measure vital biomarkers that inform the FIT protocol’s
application. By integrating real-time data on biomarkers into the FIT regimen, we can further tailor insulin
therapy, ensuring that each patient’s treatment is as precise as their unique physiological responses.
The Biomarkers of Diabetes: A Supporting Cast
While the FIT protocol takes center stage, the biomarkers monitored by the minilab play a crucial supporting
role. These indicators provide insights into individual metabolic states, offering a data-rich backdrop against
which the FIT protocol can be fine-tuned for optimal effectiveness.
The Unification of Tradition and Innovation
Our approach marries the tried-and-true legacy of insulin with the innovative prospects of both biomimicry and
personalized medicine. The FIT protocol is the heart of our strategy, while Precision Diabetes Care represents
the veins through which innovation flows, nourishing our efforts with valuable data and insights.
Globalizing Diabetes Care: The Digital Clinician and Patient Platform
In parallel with our clinical endeavors, the Institute is ardently working on its third pillar of research: the global
expansion of our Diabetes Precision Care platform through a state-of-the-art digital infrastructure. This
initiative, embodied by our pioneering “Digital Clinician and Patient” platform, is set to redefine the
accessibility of diabetes care. Our ambition is to leverage a highly secure, decentralized, all-digital platform to
democratize the standards of care worldwide. By doing so, we aim to ensure that every individual receives the
highest quality of care irrespective of geographic location. This digital clinician and patient ecosystem are not
just a tool for today but a foundation for tomorrow, capable of instantaneously integrating future innovations and
treatment protocols across the globe. Through this digital conduit, we envision a world where the latest
advancements in diabetes care are within reach of all who need them, fostering a new age of healthcare equity
and excellence.
A Call to Action: Support FIT and Precision Care
We invite you to be a part of the solution. If you are a
patient, healthcare professional, or advocate join us in this pivotal moment in diabetes care. Your support to
advance research for the FIT protocol as well as the precision diagnostics can and will change the devastating
impact of diabetes both globally and for someone you love. Please go to tphinstitue.org (a 501c3) to learn more
and contribute abundantly.
Conclusion:
The FIT Protocol as Our Guiding Star
As we forge ahead, the FIT protocol remains our guiding star, with Precision Diabetes Care providing additional
light to illuminate our path. Together, these approaches promise to redefine the landscape of diabetes treatment,
offering hope for a future where diabetes is not a burden, but a condition met with powerful, personalized
solutions. By focusing on prevention, remission of complications, and economic sustainability, we are paving
the way for a future where better health is synonymous with more affordable care.
